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ドクターシーラボの化粧品を使い始めてから、もう7~8年くらいになると思います。
昔は、肌荒れに悩んだり、肌が乾燥して困ったりしましたが、ドクターシーラボを使い始めてから、一度も肌荒れや乾燥の悩みはありません。
子どもがまだ小さくて、なかなか買い物に行かれなかった時に、いつでもネットで買い物ができる通販化粧品を使い始めました。
まず1社のものを試してみたら、悪いわけではないのですが、何だかあまり肌の調子が良くないような気がして、他の会社のものに変えてみました。
すると、今度はもっと肌の調子が悪くなってしまいました。
3社目にためしてみたのがドクターシーラボです。
アクアコラーゲンゲルが良さそうだな、と思って使い始めたところ、肌の調子が良くなりました。
スポンサードリンク
さらに良かったのは、真冬でも、乾燥して肌がカサカサになることがなくなったのです。
私は今まで、秋から冬は肌がカサカサになるのが当たり前だと思っていたのですが、アクアコラーゲンゲルを使い始めてから、そんなことはまったくなくなりました。
それ以来、基礎化粧品はすべてドクターシーラボの物を使っています。
他の通販化粧品に比べて値段は高めですが、値段の違いは品質の違いなんだと思いました。
ドクターシーラボを使い始めたころは、まだ、シワやたるみ、シミなどの悩みはありませんでしたが、年齢とともにそういう悩みも出てきました。
そこで、今はドクターシーラボのエイジングケア用の基礎化粧品を使っています。
アクアコラーゲンゲルエンリッチソフトは、肌がピーンとはる感じもいいし、本当にお肌がぷるぷるになります。
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or a pharmaceutically acceptable salt thereof, wherein X is N or C R 3; R 1 is R, R D, or OR; R 2 is H, R C, N R C O Cy 2, N R S O 2 Cy 2, N R Cy 2, OCy 2, SCy 2, or Cy 2; R 3 is H, halogen, or C 1 6 aliphatic; or R 2 and R 3 are taken together with their intervening atoms to form a 4 7 membered partially unsaturated or aromatic ring having 0 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; wherein said ring is substituted with m instances of R 4; each of Cy 1 and Cy 2 is independently phenyl; a 5 6 membered monocyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; an 8 10 membered bicyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; a 3 7 membered saturated or partially unsaturated heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur; or a 3 7 membered saturated or partially unsaturated monocyclic carbocyclic ring; or a 7 12 membered saturated or partially unsaturated bicyclic heterocyclic ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, wherein Cy 1 is substituted with n instances of R 5; and; wherein Cy 2 is substituted with p instances of R 6; L 1 is a covalent bond or a C 1 4 bivalent saturated or unsaturated, straight or branched hydrocarbon chain wherein one or two methylene units of the chain are optionally and independently replaced by C R 7 2, N R, N R C O, C O N R, N R S O 2, S O 2 N R, O, C O, OC O, C O O, S, S O or S O 2; each instance of R 4, R 5, R 6, and R 7 is independently R A or R B, and is substituted by q instances of R C; each instance of R A is independently oxo, halogen, CN, NO 2, OR, OR D, SR, NR 2, S O 2 R, S O 2 NR 2, S O R, S O NR 2, C O R, C O OR, C O NR 2, C O N R OR, OC O R, OC O NR 2, N R C O OR, N R C O R, N R C O NR 2, N R C NR NR 2, N R S O 2 NR 2, or N R S O 2 R; each instance of R B is independently C 1 6 aliphatic; phenyl; a 5 6 membered monocyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; an 8 10 membered bicyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; a 3 7 membered saturated or partially unsaturated carbocyclic ring; a 3 7 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur; or a 7 12 membered saturated or partially unsaturated bicyclic heterocyclic ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; each instance of R C is independently oxo, halogen, CN, NO 2, OR, SR, NR 2, S O 2 R, S O 2 NR 2, S O R, S O NR 2, C O R, C O OR, C O NR 2, C O N R OR, OC O R, OC O NR 2, N R C O OR, N R C O R, N R C O NR 2, N R C NR NR 2, N R S O 2 NR 2, or N R S O 2 R or an optionally substituted group selected from C 1 6 aliphatic, phenyl, a 3 7 membered saturated or partially unsaturated heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and a 5 6 membered heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; R D is a C 1 4 aliphatic group wherein one or more hydrogens are replaced by deuterium; each R is independently hydrogen, or an optionally substituted group selected from C 1 6 aliphatic, phenyl, a 3 7 membered saturated or partially unsaturated heterocyclic having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and a 5 6 membered heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, or two R groups on the same nitrogen are taken together with their intervening atoms to form a 4 7 membered saturated, partially unsaturated, or heteroaryl ring having 0 3 heteroatoms, in addition to the nitrogen, independently selected from nitrogen, oxygen, and sulfur; and each of m, n, p, and q is independently 0, 1, 2, 3, or 4 buy cialis online